Article
Concentrations of ochratoxin A in the urine of endemic nephropathy patients and controls in Bulgaria: lack of detection of 4-hydroxyochratoxin A.
IARC scientific publications - 1 Jan 1991
Castegnaro M, Maru V, Petkova-Bocharova T, Nikolov I, Bartsch H
Abstract excerpt
Ochratoxin A has been detected more frequently and at higher levels as a contaminant in staple food consumed by subjects affected by Balkan endemic nephropathy or urinary tract tumours in the Vratza district (Bulgaria) than in samples from control populations in and outside the endemic area. Serum from patients with Balkan endemic nephropathy also contained ochratoxin A more frequently and at higher levels than...
Topics
- Animals
- Balkan Nephropathy
- Biotransformation
- Bulgaria
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Disease Susceptibility
- Food Contamination
- Genetic Predisposition to Disease
- Humans
