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Article

Transplantation of mesenchymal stem cells in a canine disc degeneration model

17 Jan 2008

Abstract excerpt

Transplantation of mesenchymal stem cells (MSCs) is effective in decelerating disc degeneration in small animals; much remains unknown about this new therapy in larger animals or humans. Fas-ligand (FasL), which is only found in tissues with isolated immune privilege, is expressed in IVDs, particularly in the nucleus pulposus (NP). Maintaining the FasL level is important for IVD function. This study evaluated...

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PMID: 18203202
DOI: 10.1002/jor.20584

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