Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stromal support augments extended long-term ex vivo expansion of hemopoietic progenitor cells.

Leukemia - 1 Sept 2001

Kusadasi N, Koevoet J L, van Soest P L, Ploemacher R E

Abstract excerpt

Current technology to numerically expand hemopoietic stem/progenitor cells (HSPC) ex vivo within 1 to 2 weeks is insufficient to warrant significant gain in reconstitution time following their transplantation. In order to more stringently test the parameters affecting HSPC expansion, we followed ex vivo cultures of CD34+-selected umbilical cord blood (UCB) HSPC for up to 10 weeks and investigated the effects of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-ribosyl Cyclase
Share to ADP-ribosyl Cyclase 1
Share to Antigens, CD34

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antigens, Differentiation

Share to Mice, Inbred NOD

Share to Serum Albumin, Bovine

Share to Stem Cell Factor

Share to Thrombopoietin

Source

Identifiers

PMID: 11516095
DOI: 10.1038/sj.leu.2402204

Genes

CD34
TPO
CD38
IL6
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stromal support augments extended long-term ex vivo expansion of hemopoietic progenitor cells.PMID 11516095Read ↗

Quantitative Analysis Reveals Expansion of Human Hematopoietic Repopulating Cells After Short-term Ex Vivo CultureSemantic proximity Read ↗

Highly Efficient Ex Vivo Expansion of Human Hematopoietic Stem Cells Using Delta1‐Fc Chimeric ProteinSemantic proximity Read ↗

Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factorSemantic proximity Read ↗

Interleukin 3 Improves the Ex Vivo Expansion of Primitive Human Cord Blood Progenitor Cells and Maintains the Engraftment Potential of SCID Repopulating CellsSemantic proximity Read ↗

Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium.Semantic proximity Read ↗

Ex vivo expansion potential of murine hematopoietic stem cells is a rare property only partially predicted by phenotype.Semantic proximity Read ↗

Expansion of hematopoietic stem cells for transplantation: current perspectivesSemantic proximity Read ↗

Ex vivo expansion of umbilical cord blood hematopoietic progenitor cells by combinations of cytokines.Semantic proximity Read ↗

Characterization of Serum-Free Ex Vivo–Expanded Hematopoietic Stem Cells Derived from Human Umbilical Cord Blood CD133 <sup>+</sup> CellsSemantic proximity Read ↗

Expansion on Stromal Cells Preserves the Undifferentiated State of Human Hematopoietic Stem Cells Despite Compromised Reconstitution AbilitySemantic proximity Read ↗

Cocultivation of umbilical cord blood cells with endothelial cells leads to extensive amplification of competent CD34+CD38- cells.Semantic proximity Read ↗

Differential kinetics of primitive hematopoietic cells assayed in vitro and in vivo during serum-free suspension culture of CD34+ blood progenitor cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.