Analysis of the role of 5' regulatory mutations in the activation of quiescent metallothionein genes after carcinogen treatment.

Article

Analysis of the role of 5' regulatory mutations in the activation of quiescent metallothionein genes after carcinogen treatment.

Gene expression - 1 Jan 1991

Aguilar-Cordova E, Lebovitz R M, Lieberman M W

Abstract excerpt

S49 are mouse thymic lymphoma cells which do not express the two closely linked mouse metallothionein (MT) genes; however, previous studies demonstrated that treatment of S49 cells with chemical carcinogens or ultraviolet irradiation can activate these quiescent genes. To determine if activation...

Topics

Animals
Base Sequence
Carcinogens
Metallothionein
Mice
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Regulatory Sequences, Nucleic Acid
Tumor Cells, Cultured

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