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Article

Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: involvement of host cellular factors.

Journal of virology - 1 Mar 2008

Wang Yan, Li Hong, Tang Qiyi, Maul Gerd G, Yuan Yan

Abstract excerpt

Herpesvirus lytic DNA replication requires both the cis-acting element, the origin, and trans-acting factors, including virally encoded origin-binding protein, DNA replication enzymes, and auxiliary factors. Two lytic DNA replication origins (ori-Lyt) of Kaposi's sarcoma-associated herpesvirus (KSHV) have been identified, and two virally encoded proteins, namely, RTA and K8, have been shown to bind to the...

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Share to Chromatin Immunoprecipitation
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Replication

Share to DNA, Viral

Share to Electrophoresis, Polyacrylamide Gel

Share to Fluorescent Antibody Technique

Share to Herpesvirus 8, Human

Share to Tandem Mass Spectrometry

Source

Open in PubMed Open full text

Identifiers

PMID: 18199640
DOI: 10.1128/JVI.01319-07
PMCID: PMC2259006

Genes

MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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