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Article

Key Role for Clumping Factor B in Staphylococcus aureus Nasal Colonization of Humans

8 Jan 2008

Abstract excerpt

BACKGROUND: Staphylococcus aureus permanently colonizes the vestibulum nasi of one-fifth of the human population, which is a risk factor for autoinfection. The precise mechanisms whereby S. aureus colonizes the nose are still unknown. The staphylococcal cell-wall protein clumping factor B (ClfB) promotes adhesion to squamous epithelial cells in vitro and might be a physiologically relevant colonization factor....

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PMID: 18198942
DOI: 10.1371/journal.pmed.0050017

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