Article
No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics.
The American journal of psychiatry - 1 Apr 2008
Sanders Alan R, Duan Jubao, Levinson Douglas F, Shi Jianxin, He Deli, Hou Cuiping, Burrell Gregory J, Rice John P, Nertney Deborah A, Olincy Ann, Rozic Pablo, Vinogradov Sophia, Buccola Nancy G, Mowry Bryan J, Freedman Robert, Amin Farooq, Black Donald W, Silverman Jeremy M, Byerley William F, Crowe Raymond R, Cloninger C Robert, Martinez Maria, Gejman Pablo V
Abstract excerpt
OBJECTIVE: The authors carried out a genetic association study of 14 schizophrenia candidate genes (RGS4, DISC1, DTNBP1, STX7, TAAR6, PPP3CC, NRG1, DRD2, HTR2A, DAOA, AKT1, CHRNA7, COMT, and ARVCF). This study tested the hypothesis of association of schizophrenia with common single nucleotide polymorphisms (SNPs) in these genes using the largest sample to date that has been collected with uniform clinical methods...
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