Article
Dual role of thyroid hormones in rat soleus muscle MyHC isoform expression.
Physiological research - 1 Jan 2007
Vadászová-Soukup A, Soukup T
Abstract excerpt
We have analyzed the influence of altered thyroid hormone levels on changes of MyHC protein isoforms and their mRNA transcripts in the soleus muscle of 2-, 4- and 7-month-old euthyroid (EU), hypothyroid (HY) and hyperthyroid (TH) female inbred Lewis strain rats (methimazole and T3 treatment started 3 to 4 weeks after birth). We have found that the content of the dominant MyHC 1 isoform gradually increased in the...
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