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Article

Differential expression of myosin heavy chain mRNA and protein isoforms in four functionally diverse rabbit skeletal muscles during pre- and postnatal development.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 1998

McKoy G, Léger M E, Bacou F, Goldspink G

Abstract excerpt

Myosin heavy chains (hcs) are the major determinant in the speed of contraction of skeletal muscle, and various isoforms are differentially expressed depending on the functional activity of the muscle. Using the rapid amplification of cDNA ends (3' RACE) method, we have characterised the 3' end of the embryonic, perinatal, type 1, 2a, 2x, and 2b myosin hc genes in rabbit skeletal muscle and used them as probes in...

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PMID: 9520107
DOI: 10.1002/(SICI)1097-0177(199803)211:3<193::AID-AJA1>3.0.CO;2-C

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