Article
Capillary regeneration in scleroderma: stem cell therapy reverses phenotype?
PloS one - 16 Jan 2008
Fleming Jo N, Nash Richard A, McLeod D O, Fiorentino David F, Shulman Howard M, Connolly M Kari, Molitor Jerry A, Henstorf Gretchen, Lafyatis Robert, Pritchard David K, Adams Lawrence D, Furst Daniel E, Schwartz Stephen M
Abstract excerpt
BACKGROUND: Scleroderma is an autoimmune disease with a characteristic vascular pathology. The vasculopathy associated with scleroderma is one of the major contributors to the clinical manifestations of the disease. METHODOLOGY/PRINCIPAL FINDINGS: We used immunohistochemical and mRNA in situ hybridization techniques to characterize this vasculopathy and showed with morphometry that scleroderma has true capillary...
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