Article
Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts.
Malaria journal - 14 Jan 2008
Gölnitz Uta, Albrecht Letusa, Wunderlich Gerhard
Abstract excerpt
BACKGROUND: Cytoadherence of Plasmodium falciparum-infected red blood cells is mediated by var gene-encoded P. falciparum erythrocyte membrane protein-1 and host receptor preference depends in most cases on which of the 50-60 var genes per genome is expressed. Enrichment of phenotypically homogenous parasites by panning on receptor expressing cells is fundamental for the identification of the corresponding var...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
