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Thymidylate synthase haplotype is associated with tumor recurrence in stage II and stage III colon cancer

1 Feb 2008

Abstract excerpt

BACKGROUND: Tumor recurrence after curative resection is a major problem in the management of colon cancer therapy. Identifying molecular markers for tumor recurrence is critical for successfully selecting patients who are more likely to benefit from adjuvant chemotherapy. We analyzed the value of thymidylate synthase (TS) and methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms as a prognostic marker...

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Share to Colorectal Cancer Surgical Treatments
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Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18192902
DOI: 10.1097/fpc.0b013e3282f4aea6

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