Role of hepatitis B virus genotype mixture, subgenotypes C2 and B2 on hepatocellular carcinoma: compared with chronic hepatitis B and asymptomatic carrier state in the same area.

doi:10.1093/carcin/bgm301

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Article

Role of hepatitis B virus genotype mixture, subgenotypes C2 and B2 on hepatocellular carcinoma: compared with chronic hepatitis B and asymptomatic carrier state in the same area.

Carcinogenesis - 1 Sept 2008

Yin Jianhua, Zhang Hongwei, Li Chengzhong, Gao Chunfang, He Yongchao, Zhai Yujia, Zhang Peng, Xu Ling, Tan Xiaojie, Chen Jinsong, Cheng Shuqun, Schaefer Stephan, Cao Guangwen

Abstract excerpt

The role of genotype mixture and subgenotypes remains controversial in determining the clinical outcome of chronic hepatitis B virus (HBV) infection. We aimed to determine their role on the development and the recurrence of hepatocellular carcinoma (HCC). HBV genotypes, serum viral load and hepatitis B e antigen (HBeAg) seroconversion were determined in 462 HCC patients, 234 chronic hepatitis patients and 425...

Topics

Adult
Carcinoma, Hepatocellular
Carrier State
China
DNA, Viral
Female
Genotype
Hepatitis B Surface Antigens
Hepatitis B e Antigens
Hepatitis B virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis B, Chronic

Humans

Liver Neoplasms

Male

Middle Aged

Neoplasm Recurrence, Local

Prognosis

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 18192693
DOI: 10.1093/carcin/bgm301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-18192693-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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