Article
Helicobacter pylori amoxicillin heteroresistance due to point mutations in PBP-1A in isogenic isolates
13 Jan 2008
Abstract excerpt
OBJECTIVES: To investigate the Helicobacter pylori amoxicillin resistance rate, the occurrence of heteroresistance, and their related molecular mechanisms. METHODS: Eighty-seven H. pylori-positive patients were included: 45/87 with single biopsy and 42/87 with multiple biopsies. MICs were determined, and sequencing analysis of pbp1A gene and the variable regions of seven hop porins was performed in resistant and...
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