Article
Evidence of Helicobacter pylori heterogeneity in human stomachs by susceptibility testing and characterization of mutations in drug-resistant isolates.
Scientific reports - 27 May 2024
Islam Jahirul Md, Yano Yukari, Okamoto Aoi, Matsuda Reimi, Shiraishi Masaya, Hashimoto Yusuke, Morita Nanaka, Takeuchi Hironobu, Suganuma Narufumi, Takeuchi Hiroaki
Abstract excerpt
Heterogeneity of Helicobacter pylori communities contributes to its pathogenicity and diverse clinical outcomes. We conducted drug-susceptibility tests using four antibiotics, clarithromycin (CLR), amoxicillin (AMX), metronidazole and sitafloxacin, to examine H. pylori population diversity. We also analyzed genes associated with resistance to CLR and AMX. We examined multiple isolates from 42 Japanese patients,...
Topics
Join the communities discussing this publication.