Article
Administrations of peripheral blood CD34-positive cells contribute to medial collateral ligament healing via vasculogenesis.
Stem cells (Dayton, Ohio) - 1 Mar 2008
Tei Katsumasa, Matsumoto Tomoyuki, Mifune Yutaka, Ishida Kazunari, Sasaki Ken, Shoji Taro, Kubo Seiji, Kawamoto Atsuhiko, Asahara Takayuki, Kurosaka Masahiro, Kuroda Ryosuke
Abstract excerpt
Neoangiogenesis is a key process in the initial phase of ligament healing. Adult human circulating CD34+ cells, an endothelial/hematopoietic progenitor-enriched cell population, have been reported to contribute to neoangiogenesis; however, the therapeutic potential of CD34+ cells for ligament healing is still unclear. Therefore, we performed a series of experiments to test our hypothesis that ligament healing is...
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