Article
Fracture induced mobilization and incorporation of bone marrow-derived endothelial progenitor cells for bone healing.
Journal of cellular physiology - 1 Apr 2008
Matsumoto Tomoyuki, Mifune Yutaka, Kawamoto Atsuhiko, Kuroda Ryosuke, Shoji Taro, Iwasaki Hiroto, Suzuki Takahiro, Oyamada Akira, Horii Miki, Yokoyama Ayumi, Nishimura Hiromi, Lee Sang Yang, Miwa Masahiko, Doita Minoru, Kurosaka Masahiro, Asahara Takayuki
Abstract excerpt
We recently reported that systemic administration of peripheral blood (PB) CD34+ cells, an endothelial progenitor cell (EPC)-enriched population, contributed to fracture healing via vasculogenesis/angiogenesis. However, pathophysiological role of EPCs in fracture healing process has not been fully clarified. Therefore, we investigated the hypothesis whether mobilization and incorporation of bone marrow...
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