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Article

PlGF repairs myocardial ischemia through mechanisms of angiogenesis, cardioprotection and recruitment of myo-angiogenic competent marrow progenitors.

PloS one - 1 Jan 2011

Iwasaki Hiroto, Kawamoto Atsuhiko, Tjwa Marc, Horii Miki, Hayashi Saeko, Oyamada Akira, Matsumoto Tomoyuki, Suehiro Shigefumi, Carmeliet Peter, Asahara Takayuki

Abstract excerpt

RATIONALE: Despite preclinical success in regenerating and revascularizing the infarcted heart using angiogenic growth factors or bone marrow (BM) cells, recent clinical trials have revealed less benefit from these therapies than expected. OBJECTIVE: We explored the therapeutic potential of myocardial gene therapy of placental growth factor (PlGF), a VEGF-related angiogenic growth factor, with...

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Share to Bone Marrow Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21969865
DOI: 10.1371/journal.pone.0024872
PMCID: PMC3182165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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