Article
Polymorphisms of the ghrelin/obestatin gene and ghrelin levels in Chinese children with short stature.
Clinical endocrinology - 1 Jul 2008
Zou Chao Chun, Huang Ke, Liang Li, Zhao Zheng Yan
Abstract excerpt
OBJECTIVE: To investigate the role of ghrelin and polymorphisms of ghrelin/obestatin gene in children with short stature. METHODS: A total of 117 GH deficient (GHD) and 81 idiopathic short stature (ISS) children were studied. The controls consisted of 125 age and gender-matched healthy children. The Arg51Gln, Leu72Met and Gln90Leu polymorphisms were genotyped using MassArray and total plasma ghrelin was measured...
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