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Article

Association between Growth Hormone-Insulin-Like Growth Factor-1 Axis Gene Polymorphisms and Short Stature in Chinese Children.

BioMed research international - 1 Jan 2018

Zhang Yanhong, Zhang Mei, Chu Yuntian, Ji Baolan, Shao Qian, Ban Bo

Abstract excerpt

OBJECTIVE: This study was designed to analyze the association between the growth hormone-insulin-like growth factor-1 (GH-IGF-1) axis gene polymorphisms and short stature in Chinese children. METHODS: 181 growth hormone deficiency (GHD) patients and 206 normal stature controls were enrolled to attend this study. Five single-nucleotide polymorphisms in the GH receptor (GHR) and 5 SNPs within the GH-signaling...

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Identifiers

PMID: 29687007
DOI: 10.1155/2018/7431050
PMCID: PMC5857343

Genes

GHR

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