Article
The Relationship Between Gene Polymorphism of Leptin and Leptin Receptor and Growth Hormone Deficiency.
Medical science monitor : international medical journal of experimental and clinical research - 26 Feb 2016
He Jinshui, Fang Yanling, Lin Xinfu, Zhou Huowang, Zhu Shaobo, Zhang Yugui, Yang Huicong, Ye Xiaoling
Abstract excerpt
BACKGROUND Growth hormone deficiency (GHD) is a major cause of congenital short stature. GHD patients have significantly decreased serum leptin levels, which are regulated by gene polymorphism of leptin and leptin receptor. This study thus investigated the relationship between gene polymorphism and susceptibility to GHD. MATERIAL AND METHODS A case-control study was performed using 180 GHD children in addition to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
