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Article

Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies.

PLoS genetics - 1 Jan 2008

Legrand Melanie, Forche Anja, Selmecki Anna, Chan Christine, Kirkpatrick David T, Berman Judith

Abstract excerpt

Haplotype maps (HapMaps) reveal underlying sequence variation and facilitate the study of recombination and genetic diversity. In general, HapMaps are produced by analysis of Single-Nucleotide Polymorphism (SNP) segregation in large numbers of meiotic progeny. Candida albicans, the most common human fungal pathogen, is an obligate diploid that does not appear to undergo meiosis. Thus, standard methods for...

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PMID: 18179283
DOI: 10.1371/journal.pgen.0040001
PMCID: PMC2174976

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ORC1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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