Article
Staphylococcal pericarditis, and liver and paratracheal abscesses as presentations in two new cases of interleukin-1 receptor associated kinase 4 deficiency.
The Pediatric infectious disease journal - 1 Feb 2008
Comeau Jeannette L, Lin Tong-Jun, Macken Marian B, Li Bo, Ku Cheng-Lung, von Bernuth Horst, Casanova Jean-Laurent, Issekutz Andrew C
Abstract excerpt
BACKGROUND: A deficiency in the interleukin-1 receptor activated kinase 4 (IRAK-4) has recently been associated with severe recurrent, predominantly Gram-positive bacterial infections. CLINICAL PRESENTATION: Two unrelated Canadian children with unique presentations of IRAK-4 deficiency are described. Both children had multiple Gram-positive bacterial infections, specifically Staphylococcus aureus and...
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