Article
Full structural characterization of Shigella flexneri M90T serotype 5 wild-type R-LPS and its delta galU mutant: glycine residue location in the inner core of the lipopolysaccharide.
Glycobiology - 1 Mar 2008
Molinaro Antonio, Silipo Alba, Castro Cristina De, Sturiale Luisa, Nigro Giulia, Garozzo Domenico, Bernardini Maria Lina, Lanzetta Rosa, Parrilli Michelangelo
Abstract excerpt
Shigella flexneri is a gram-negative bacterium responsible for serious enteric infections that occur mainly in the terminal ileum and colon. High interest in Shigella, as a human pathogen, is driven by its antibiotic resistance and the necessity to develop a vaccine against its infections. Vaccin...
Topics
- Carbohydrate Sequence
- Genes, Bacterial
- Glycine
- Lipopolysaccharides
- Magnetic Resonance Spectroscopy
- Molecular Sequence Data
- Mutation
- O Antigens
- Reference Standards
- Shigella flexneri
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- UTP-Glucose-1-Phosphate Uridylyltransferase