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Article

A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease.

Journal of bioinformatics and computational biology - 1 Dec 2007

Worth Catherine L, Bickerton G Richard J, Schreyer Adrian, Forman Julia R, Cheng Tammy M K, Lee Semin, Gong Sungsam, Burke David F, Blundell Tom L

Abstract excerpt

The prediction of the effects of nonsynonymous single nucleotide polymorphisms (nsSNPs) on function depends critically on exploiting all information available on the three-dimensional structures of proteins. We describe software and databases for the analysis of nsSNPs that allow a user to move f...

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PMID: 18172930
DOI: 10.1142/s0219720007003120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18172930-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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