Article
Induction of functional photoreceptor phenotype by exogenous Crx expression in mouse retinal stem cells.
Investigative ophthalmology & visual science - 1 Jan 2008
Jomary Catherine, Jones Stephen E
Abstract excerpt
PURPOSE: This study was undertaken to determine whether exogenous expression of the transcription factor Crx can promote the differentiation of mouse retinal stem cells (RSCs) into cells with a functional photoreceptor phenotype exhibiting light-sensitive properties. METHODS: RSCs isolated from mouse ciliary epithelium and maintained in serum-free culture were genetically modified by electroporation to express...
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