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Article

Iris-derived cells from adult rodents and primates adopt photoreceptor-specific phenotypes.

Investigative ophthalmology & visual science - 1 Sept 2005

Akagi Tadamichi, Akita Joe, Haruta Masatoshi, Suzuki Takuya, Honda Yoshihito, Inoue Tomoyuki, Yoshiura Shigeki, Kageyama Ryoichiro, Yatsu Takaaki, Yamada Masahiro, Takahashi Masayo

Abstract excerpt

PURPOSE: The purpose of this study was to investigate the effects of various genes related to photoreceptor development on rodent and primate iris cells and the potential of iris cells as donor cells for retinal transplantation. METHODS: Adult rat and monkey iris tissue were cultured in serum-free medium containing basic fibroblast growth factor. Gene deliveries of Crx, Nrl, NeuroD and some combinations (Crx-Nrl,...

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PMID: 16123446
DOI: 10.1167/iovs.04-1112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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