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Article

Direct interaction between Rab3D and the polymeric immunoglobulin receptor and trafficking through regulated secretory vesicles in lacrimal gland acinar cells.

American journal of physiology. Cell physiology - 1 Mar 2008

Evans Eunbyul, Zhang Wenzheng, Jerdeva Galina, Chen Chiao-Yu, Chen Xuequn, Hamm-Alvarez Sarah F, Okamoto Curtis T

Abstract excerpt

The lacrimal gland is responsible for tear production, and a major protein found in tears is secretory component (SC), the proteolytically cleaved fragment of the extracellular domain of the polymeric Ig receptor (pIgR), which is the receptor mediating the basal-to-apical transcytosis of polymeric immunoglobulins across epithelial cells. Immunofluorescent labeling of rabbit lacrimal gland acinar cells (LGACs)...

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Identifiers

PMID: 18171724
DOI: 10.1152/ajpcell.00623.2006
PMCID: PMC4046641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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