Article
Mapping of the 45M1 epitope to the C‐terminal cysteine‐rich part of the human MUC5AC mucin
21 Dec 2007
Abstract excerpt
Mucins are large glycoproteins protecting mucosal surfaces throughout the body. Their expressions are tissue-specific, but in disease states such as cystic fibrosis, inflammation and cancer, this specificity can be disturbed. MUC5AC is normally expressed in the mucous cells of the epithelia lining the stomach and the trachea, where it constitutes a major component of the gastric and respiratory mucus. A number of...
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