Association of the dopamine transporter gene and ADHD symptoms in a Canadian population-based sample of same-age twins.

doi:10.1002/ajmg.b.30677

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Article

Association of the dopamine transporter gene and ADHD symptoms in a Canadian population-based sample of same-age twins.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2008

Ouellet-Morin Isabelle, Wigg Karen G, Feng Yu, Dionne Ginette, Robaey Philippe, Brendgen Mara, Vitaro Frank, Simard Louise, Schachar Russell, Tremblay Richard E, Pérusse Daniel, Boivin Michel, Barr Cathy L

Abstract excerpt

Attention deficit hyperactivity disorder (ADHD) is the most prevalent psychiatric disorder emerging during childhood. Psychostimulant medications (e.g., methylphenidate) noticeably reduce ADHD symptoms in most children. Since methylphenidate inhibits dopamine transporter activity, the dopamine transporter gene (DAT1) was considered to be the prime candidate risk gene in ADHD. Several studies found evidence for an...

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PMID: 18165969
DOI: 10.1002/ajmg.b.30677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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