Article
A review and analysis of the relationship between neuropsychological measures and DAT1 in ADHD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2008
Rommelse Nanda N J, Altink Marieke E, Arias-Vásquez Alejandro, Buschgens Cathelijne J M, Fliers Ellen, Faraone Stephen V, Buitelaar Jan K, Sergeant Joseph A, Franke Barbara, Oosterlaan Jaap
Abstract excerpt
Meta-analyses indicate that the gene coding for the dopamine transporter (DAT1 or SLC6A3) is associated with an increased risk for ADHD. The mechanisms of this gene for ADHD are unclear. We systematically reviewed studies linking the VNTR in the 3' UTR of the DAT1 to neurophysiological and neuropsychological measures. In addition, a broad set of executive/cognitive and motor tests was administered to 350 children...
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