Article
Analysis of YfgL and YaeT interactions through bioinformatics, mutagenesis, and biochemistry.
Journal of bacteriology - 1 Mar 2008
Vuong Phu, Bennion Drew, Mantei Jeremy, Frost Danielle, Misra Rajeev
Abstract excerpt
In Escherichia coli, YaeT, together with four lipoproteins, YfgL, YfiO, NlpB, and SmpA, forms a complex that is essential for beta-barrel outer membrane protein biogenesis. Data suggest that YfgL and YfiO make direct but independent physical contacts with YaeT. Whereas the YaeT-YfiO interaction needs NlpB and SmpA for complex stabilization, the YaeT-YfgL interaction does not. Using bioinformatics, genetics, and...
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