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Article

Genetic variability in estrogen disposition: Potential clinical implications for neuropsychiatric disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2010

Grover Sandeep, Talwar Puneet, Baghel Ruchi, Kaur Harpreet, Gupta Meenal, Gourie-Devi Mandaville, Bala Kiran, Sharma Sangeeta, Kukreti Ritushree

Abstract excerpt

Variability in the physiological levels of neuroactive estrogens is widely believed to play a role in predisposition to several disorders of the central nervous system. Local biosynthesis of estrogens in the brain as well as their circulating serum levels are known to contribute to this pool of neuroactive steroids. It has been well accepted that estrogens modulate neuronal functions by affecting genesis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20886541
DOI: 10.1002/ajmg.b.31119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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