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Article

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis.

Arthritis and rheumatism - 1 Apr 2006

De Bari Cosimo, Dell'Accio Francesco, Vanlauwe Johan, Eyckmans Jeroen, Khan Ilyas M, Archer Charles W, Jones Elena A, McGonagle Dennis, Mitsiadis Thimios A, Pitzalis Costantino, Luyten Frank P

Abstract excerpt

OBJECTIVE: To investigate whether periosteal cells from adult humans have features of multipotent mesenchymal stem cells (MSCs) at the single-cell level. METHODS: Cell populations were enzymatically released from the periosteum of the proximal tibia obtained from adult human donors and then expanded in monolayer. Single-cell-derived clonal populations were obtained by limiting dilution. Culture-expanded...

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PMID: 16575900
DOI: 10.1002/art.21753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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