Article
Characterization of HIV type 1 reverse transcriptase mutations in infants infected by mothers who received peripartum nevirapine prophylaxis in Jos, Nigeria.
AIDS research and human retroviruses - 1 Dec 2007
Ojesina Akinyemi I, Mullins Christopher, Imade Godwin, Samuels Jay, Sankalé Jean-Louis, Pam Sunday, Sagay Solomon, Idoko John, Kanki Phyllis J
Abstract excerpt
This study was carried out to characterize HIV-1 reverse transcriptase (RT) mutations in vertically infected infants in Jos, Nigeria. DNA was extracted from peripheral blood mononuclear cells of 102 infants, aged 0 to 6 months, born to HIV-1-infected mothers who had received peripartum single-dose nevirapine prophylaxis. PCR-based diagnosis revealed that 14 infants (13.7%) were infected with HIV-1. Phylogenetic...
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