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Characterizing HIV-1 Genetic Subtypes and Drug Resistance Mutations among Children, Adolescents and Pregnant Women in Sierra Leone.

Genes - 26 Aug 2021

Yendewa George A, Lakoh Sulaiman, Yendewa Sahr A, Bangura Khadijah, Tabernilla Andrés, Patiño Lucia, Jiba Darlinda F, Vandy Alren O, Massaquoi Samuel P, Osório Nuno S, Deen Gibrilla F, Sahr Foday, Salata Robert A, Poveda Eva

Abstract excerpt

Human immunodeficiency virus (HIV) drug resistance (HIVDR) is widespread in sub-Saharan Africa. Children and pregnant women are particularly vulnerable, and laboratory testing capacity remains limited. We, therefore, used a cross-sectional design and convenience sampling to characterize HIV subtypes and resistance-associated mutations (RAMs) in these groups in Sierra Leone. In total, 96 children (age 2-9 years,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34573296
DOI: 10.3390/genes12091314
PMCID: PMC8469552

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