Article
The application of computational methods to the study of enzyme catalysis by triose-phosphate isomerase and stabilities of variants of bacteriophage T4 lysozyme.
Ciba Foundation symposium - 1 Jan 1991
Kollman P A, Daggett V, Dang L X
Abstract excerpt
We review our research on triose-phosphate isomerase and bacteriophage T4 lysozyme. In our studies over the last ten years we have used electrostatic potentials, computer graphics, quantum mechanics, molecular mechanics, molecular dynamics and free energy calculations to try to understand why tri...
Topics
- Amino Acid Sequence
- Binding Sites
- Catalysis
- Dihydroxyacetone Phosphate
- Mathematical Computing
- Models, Molecular
- Molecular Sequence Data
- Muramidase
- Mutation
- Protein Conformation
- Sequence Homology, Nucleic Acid
- T-Phages
- Triose-Phosphate Isomerase