Article
Metabolic analysis of galactose toxicity in Escherichia coli with 2-deoxygalactose as the probe.
Indian journal of biochemistry & biophysics - 1 Jan 2000
Raut N, Bhaduri A
Abstract excerpt
Biochemical basis of galactose toxicity has been studied in gal T mutants (CGSC 4974) using 2-deoxygalactose, a non-metabolizable analogue of galactose, as the probe. It is found that biochemical features of toxicity in wild type cells either with 2-deoxygalactose or with 2-deoxyglucose are very similar to the picture obtained with gal T mutants and the observed bacteriostasis is probably due to futile...
Topics
- Escherichia coli
- Fucose
- Galactose
- Molecular Probes
- Mutation
- Phosphorylation