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Article

The effect of NQO1 polymorphism on the inflammatory response in cardiopulmonary bypass.

Cell biochemistry and function - 1 Jun 2008

Isbir C Selim, Ergen Arzu, Tekeli Atike, Zeybek Umit, Gormus Uzay, Arsan Sinan

Abstract excerpt

Cardiopulmonary bypass (CPB) has been associated with systemic inflammatory response syndrome (SIRS). Endothelial dysfunction related to non-laminar flow during CPB is known to play a key role in this complex pathology. Antioxidant response element (ARE) dependent NAD(P)H:quinone oxidoreductase 1 (NQO1) promoter is a regulatory element involved in the anti-inflammatory mechanism in vasculature exposed to...

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Share to NQO1 gene
Share to Genotype
Share to Inflammation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-6

Share to NAD(P)H Dehydrogenase (Quinone)

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 18098117
DOI: 10.1002/cbf.1456

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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