Article
Canine population structure: assessment and impact of intra-breed stratification on SNP-based association studies.
PloS one - 19 Dec 2007
Quignon Pascale, Herbin Laetitia, Cadieu Edouard, Kirkness Ewen F, Hédan Benoit, Mosher Dana S, Galibert Francis, André Catherine, Ostrander Elaine A, Hitte Christophe
Abstract excerpt
BACKGROUND: In canine genetics, the impact of population structure on whole genome association studies is typically addressed by sampling approximately equal numbers of cases and controls from dogs of a single breed, usually from the same country or geographic area. However one way to increase th...
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