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Article

Estrogen receptor alpha polymorphism modifies the association between childhood exercise and bone mass: follow-up study.

Pediatric exercise science - 1 Nov 2007

Suuriniemi Miia, Suominen Harri, Mahonen Anitta, Alen Markku, Cheng Sulin

Abstract excerpt

This follow-up study confirms our previous findings that the ER-alpha PvuII polymorphism (Pp) modulates the association between exercise and bone mass. The differences in bone properties of girls with consistently low physical activity (LLPA) and consistently high physical activity (HHPA) were evident only in those bearing the heterozygote ER-alpha genotype (Pp). In particular, areal bone mineral density of the...

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PMID: 18089911
DOI: 10.1123/pes.19.4.444

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