Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cardiac sodium channel mutation in atrial fibrillation.

Heart rhythm - 1 Jan 2008

Ellinor Patrick T, Nam Edwin G, Shea Marisa A, Milan David J, Ruskin Jeremy N, MacRae Calum A

Abstract excerpt

BACKGROUND: Mutations in the sodium channel SCN5A have been implicated in many cardiac disorders, including the long QT syndrome, Brugada syndrome, conduction system disease, and dilated cardiomyopathy with atrial arrhythmias. OBJECTIVE: In view of the pleiotropic effects of SCN5A mutations, the purpose of this study was to examine a cohort of patients with familial atrial fibrillation (AF) for mutations in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrial Fibrillation
Share to Heart Atria
Share to Muscle Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to NAV1.5 Voltage-Gated Sodium Channel

Share to Pilot Projects

Share to Sodium Channels

Share to Stroke Volume

Share to Ultrasonography

Source

Identifiers

PMID: 18088563
DOI: 10.1016/j.hrthm.2007.09.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cardiac sodium channel mutation in atrial fibrillation.PMID 18088563Read ↗

Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation.Semantic proximity Read ↗

Mutations in sodium channel β1- and β2-subunits associated with atrial fibrillation.Semantic proximity Read ↗

Sodium channel mutations and arrhythmias.Semantic proximity Read ↗

Cardiac sodium channelopathy associated with SCN5A mutations: electrophysiological, molecular and genetic aspects.Semantic proximity Read ↗

A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation.Semantic proximity Read ↗

Gain-of-function mutation in SCN5A causes ventricular arrhythmias and early onset atrial fibrillationSemantic proximity Read ↗

A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation.Semantic proximity Read ↗

Inherited sodium channelopathies: a continuum of channel dysfunction.Semantic proximity Read ↗

The cardiac sodium channel gene SCN5A and its gene product NaV1.5: Role in physiology and pathophysiology.Semantic proximity Read ↗

[Inherited cardiac diseases caused by Nav1.5 sodium channel mutations].Semantic proximity Read ↗

Genetic Na+ channelopathies and sinus node dysfunction.Semantic proximity Read ↗

SCN5A Variants: Association With Cardiac DisordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.