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Article

Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays

18 Dec 2007

Abstract excerpt

CpG island arrays represent a high-throughput epigenomic discovery platform to identify global disease-specific promoter hypermethylation candidates along bladder cancer progression. DNA obtained from 10 pairs of invasive bladder tumours were profiled vs their respective normal urothelium using differential methylation hybridisation on custom-made CpG arrays (n=12 288 clones). Promoter hypermethylation of 84...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 18087279
DOI: 10.1038/sj.bjc.6604143

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