Article
A novel epigenetic phenotype associated with the most aggressive pathway of bladder tumor progression.
Journal of the National Cancer Institute - 5 Jan 2011
Vallot Céline, Stransky Nicolas, Bernard-Pierrot Isabelle, Hérault Aurélie, Zucman-Rossi Jessica, Chapeaublanc Elodie, Vordos Dimitri, Laplanche Agnès, Benhamou Simone, Lebret Thierry, Southgate Jennifer, Allory Yves, Radvanyi François
Abstract excerpt
BACKGROUND: Epigenetic silencing can extend to whole chromosomal regions in cancer. There have been few genome-wide studies exploring its involvement in tumorigenesis. METHODS: We searched for chromosomal regions affected by epigenetic silencing in cancer by using Affymetrix microarrays and real-...
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