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Article

Co-Circulation and Evolution of Polioviruses and Species C Enteroviruses in a District of Madagascar

10 Dec 2007

Abstract excerpt

Between October 2001 and April 2002, five cases of acute flaccid paralysis (AFP) associated with type 2 vaccine-derived polioviruses (VDPVs) were reported in the southern province of the Republic of Madagascar. To determine viral factors that favor the emergence of these pathogenic VDPVs, we analyzed in detail their genomic and phenotypic characteristics and compared them with co-circulating enteroviruses. These...

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PMID: 18085822
DOI: 10.1371/journal.ppat.0030191

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