Article
Conversion of plasma membrane topology during epithelial tube connection requires Arf-like 3 small GTPase in Drosophila.
Mechanisms of development - 1 Jan 2000
Kakihara Ken, Shinmyozu Kaori, Kato Kagayaki, Wada Hosei, Hayashi Shigeo
Abstract excerpt
The development of tubular organs often involves the hollowing of cells into a torus (doughnut shape), as observed in blood vessel formation in vertebrates and tracheal development in insects. During the fusion of Drosophila tracheal branches, fusion cells located at the tip of migrating branches contact each other and form intracellular luminal cavities on opposite sides of the cells that open to connect the...
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