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Article

Inhibition of Src reduces gemcitabine-induced cytotoxicity in human pancreatic cancer cell lines.

Cancer letters - 18 Feb 2008

Ichihara Naoto, Kubota Yoshitsugu, Kitanaka Akira, Tanaka Terukazu, Taminato Tomohiko

Abstract excerpt

In the present study, we examined the role of Src in gemcitabine-induced cell growth suppression in human pancreatic cancer cell lines. In two human pancreatic cancer cell lines, PK-9 and MIA PaCa-2, we found that a selective Src protein tyrosine kinase inhibitor, PP2, inhibited gemcitabine-induc...

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Source

Identifiers

PMID: 18078709
DOI: 10.1016/j.canlet.2007.10.035

Genes

MIA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18078709-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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