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Article

Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model.

Molecular microbiology - 1 Jan 2008

Sayeed Sameera, Uzal Francisco A, Fisher Derek J, Saputo Juliann, Vidal Jorge E, Chen Yue, Gupta Phalguni, Rood Julian I, McClane Bruce A

Abstract excerpt

Clostridium perfringens type C isolates, which cause enteritis necroticans in humans and enteritis and enterotoxaemias of domestic animals, typically produce (at minimum) beta toxin (CPB), alpha toxin (CPA) and perfringolysin O (PFO) during log-phase growth. To assist development of improved vaccines and therapeutics, we evaluated the contribution of these three toxins to the intestinal virulence of type C...

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Source

Identifiers

PMID: 18078439
DOI: 10.1111/j.1365-2958.2007.06007.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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