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Article

NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens

5 Feb 2008

Abstract excerpt

For over 30 years a phospholipase C enzyme called alpha-toxin was thought to be the key virulence factor in necrotic enteritis caused by Clostridium perfringens. However, using a gene knockout mutant we have recently shown that alpha-toxin is not essential for pathogenesis. We have now discovered a key virulence determinant. A novel toxin (NetB) was identified in a C. perfringens strain isolated from a chicken...

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Identifiers

PMID: 18266469
DOI: 10.1371/journal.ppat.0040026

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Related research

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NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringensPMID 18266469Read ↗

Association between avian necrotic enteritis and<i>Clostridium perfringens</i>strains expressing NetB toxinSemantic proximity Read ↗

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Characterization of Clostridium perfringens recovered from broiler chicken affected by necrotic enteritisSemantic proximity Read ↗

The pathogenesis of necrotic enteritis in chickens: what we know and what we need to know: a reviewSemantic proximity Read ↗

Structural and Functional Analysis of the Pore-Forming Toxin NetB from Clostridium perfringensSemantic proximity Read ↗

Perfrin, a novel bacteriocin associated with netB positive Clostridium perfringens strains from broilers with necrotic enteritisSemantic proximity Read ↗

Characterization of Virulent netB+/tpeL+Clostridium perfringens Strains from Necrotic Enteritis–Affected Broiler Chicken FarmsSemantic proximity Read ↗

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