Article
Mutations in a small region of the exportin Crm1p disrupt the daughter cell-specific nuclear localization of the transcription factor Ace2p in Saccharomyces cerevisiae.
Biology of the cell - 1 Jun 2008
Bourens Myriam, Racki Waldemar, Bécam Anne-Marie, Panozzo Cristina, Boulon Séverine, Bertrand Edouard, Herbert Christopher J
Abstract excerpt
BACKGROUND INFORMATION: The CBK1 gene of Saccharomyces cerevisiae encodes a protein kinase that is a member of the NDR (nuclear Dbf2-related) family of protein kinases, which are involved in morphogenesis and cell proliferation. Previous studies have shown that deletion of CBK1 leads to a loss of polarity and the formation of large aggregates of cells. This aggregation phenotype is due to the loss of the daughter...
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